American Journal of Clinical and Experimental Medicine

Volume 3, Issue 1, January 2015

  • Monitoring Microbiological Response to Antituberculosis Therapy by Real-Time PCR

    Yadi Yasir, Ressy Dwiyanti, Muhammad Sabir, Andini Febrianty, Ahmad Adhyka, Nur Indah Purnamasari, Muhammad Reza Primaguna, Nataniel Tandirogang, Masyhudi Amir, Syamsu Rijal, Rosdiana Natzir, SutjiPratiwi Rahardjo, Mochammad Hatta

    Issue: Volume 3, Issue 1, January 2015
    Pages: 1-5
    Received: 19 October 2014
    Accepted: 6 November 2014
    Published: 19 January 2015
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    Abstract: Background: M. tuberculosis grows slowly and requires several weeks to detect in clinical specimens using standard culture techniques. Messenger RNA is more rapidly destroyed in cells than rRNA or genomic DNA, assays that target mycobacterial mRNA better reflect mycobacterial viability. Therefore we evaluated performance of mRNA for monitoring resp... Show More
  • Microbiology of Diabetic Foot Ulcer with Special Reference to ESBL Infections

    Mohammad Zubair, Abida Malik, Jamal Ahmad

    Issue: Volume 3, Issue 1, January 2015
    Pages: 6-23
    Received: 7 December 2014
    Accepted: 17 December 2014
    Published: 26 January 2015
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    Abstract: Chronic foot wounds represent an increasing burden to healthcare systems as the age of the population increases. The deep dermal tissues of all chronic wounds harbor microorganisms, however, the precise interaction between microbes in the wounds and impaired healing is unknown. With regard to antibiotic therapy, there is a lack of evidence concerni... Show More
  • Computed Tomography Assessment of the Vascularization Degree of Hepatocellular Carcinoma in the Noncirrhotic Liver

    Ulyana N. Tumanova, Grigoriy G. Karmazanovsky, Alexander I. Shchyogolev

    Issue: Volume 3, Issue 1, January 2015
    Pages: 24-31
    Received: 31 December 2014
    Accepted: 15 January 2015
    Published: 28 January 2015
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    Abstract: An important CT-characteristic at a diagnostic of liver tumors is the determination of its vascularity. To study the characteristics of blood tissue of hepatocellular carcinoma (HCC) with different degrees of differentiation by CT. The work is based on the clinical and morphological comparisons performed in 55 patients (34 men and 21 women aged 15-... Show More
  • Rabbit Snake-Bite Model to Assess Safety and Efficacy of Anti Viper Chicken Antibodies (IgY)

    Lissy Kalliyana Krishnan, Juliet Baby Saroja, Madhumati Rajalingam, Vimala John, Mohanan Parayathala Valappil, Harikrishnan Vijayakumar Sreelatha

    Issue: Volume 3, Issue 1, January 2015
    Pages: 32-38
    Received: 17 October 2014
    Accepted: 28 October 2014
    Published: 2 February 2015
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    Abstract: Infusion of mammalian antivenom is considered to be the best available treatment for snake bites; but, production of cost-effective IgG in pure form is challenging. Purification of egg yolk immunoglobulins (IgY) raised against various toxins has been found to be relatively easier. But to use IgY for therapeutic purpose its efficacy and safety need ... Show More
  • Serum Angiopoietin-2 as Marker of Plasma Leakage in Dengue Viral Infection

    Novie Homenta Rampengan, Dasril Daud, Sarah Warouw, Idham Jaya Ganda

    Issue: Volume 3, Issue 1, January 2015
    Pages: 39-43
    Received: 6 January 2015
    Accepted: 18 January 2015
    Published: 2 February 2015
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    Abstract: Background. The immunopathology of DHF/DSS is yet completely understood. Angiopoietin-2 (Ang-2) produced by endothelial cell could promote vascular leakage by disrupting endothelial junction. Few studies reported the role of Ang-2 in dengue viral infection. Objective. To study the role of Ang-2 in promoting vascular leakage in dengue viral infectio... Show More
  • Mean Values, Normal Limits and Sex Differences of Anthropometry of Young Adults in a University Community in Nigeria

    Oluwadare Ogunlade, Olusoji Adeola Adalumo

    Issue: Volume 3, Issue 1, January 2015
    Pages: 44-47
    Received: 28 December 2014
    Accepted: 26 January 2015
    Published: 2 February 2015
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    Abstract: This study assessed the weight, height, body mass index (BMI) and body surface area (BSA) of young adults at Ile-Ife with a view of determining the mean values, normal limits and sex differences in the anthropometric parameters. Four hundred and eighty four (242 males and 242 females) subjects aged between 18-41 years (inclusive) were recruited for... Show More
  • Correlation of Serum IL-4 Levels in New and MDR Tuberculosis Patients

    Nazish Fatima, Mohammad Shameem, Nabeela, Parvez A. Khan, H. M. Khan

    Issue: Volume 3, Issue 1, January 2015
    Pages: 48-51
    Received: 24 November 2014
    Accepted: 17 December 2014
    Published: 6 February 2015
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    Abstract: Mycobacterium tuberculosis (Mtb) infects approximately one third of world population. Many cytokines are produced during tuberculosis, with predominance of Th1 cytokines during the early stage and Th2 cytokines in the later stages of the infection. Most studies on cytokines during TB are from ‘in vitro’-stimulated lymphoid cells with few reports on... Show More